LPN Programs in South Carolina: Schools, Requirements & Salary (2026)
South Carolina LPN programs prepare students for a stable and rewarding nursing career in a state with growing healthcare demand. With approximately 10,440 LPNs employed across the state and a median salary of $48,470, South Carolina offers solid employment opportunities for practical nurses — particularly in the Charleston, Columbia, and Greenville metro areas. LPN schools in South Carolina are available through the state’s technical college system, with programs accessible from the Upstate to the Lowcountry. The SC Board of Nursing oversees all LPN licensure requirements. If you’re searching for LPN classes in South Carolina, this guide covers the top programs, state requirements, salary outlook, and how to get started. South Carolina is also a member of the Nurse Licensure Compact, giving licensed LPNs the flexibility to practice in dozens of other states.
LPN Salary in South Carolina
The median annual salary for LPNs in South Carolina is $48,470, which is $11,260 below the national median of $59,730. The state employs approximately 10,440 LPNs, with projected job growth of 5% through 2032.
Top-Paying Cities in South Carolina
| City | Median Salary |
|---|---|
| Charleston | $50,200 |
| Columbia | $49,100 |
| Greenville | $48,800 |
| Myrtle Beach | $47,500 |
For detailed salary percentiles and metro-area data, see our complete LPN salary guide.
How to Become an LPN in South Carolina
To practice as an LPN in South Carolina, you must complete a state-approved practical nursing program and pass the NCLEX-PN exam. Here's the process:
Complete prerequisites
High school diploma or GED, CPR/BLS certification, passing TEAS or HESI entrance exam score, background check, and current immunizations.
Enroll in an approved LPN program
Choose a program approved by the SC Board of Nursing. South Carolina LPN programs typically require 600+ clinical hours across acute care, long-term care, and community health settings.
Complete coursework and clinical rotations
Programs cover nursing fundamentals, pharmacology, anatomy, medical-surgical nursing, pediatrics, and mental health. Clinical rotations take place at hospitals, nursing homes, and clinics across South Carolina.
Pass the NCLEX-PN
After graduating, register with the SC Board of Nursing and pass the NCLEX-PN exam to earn your LPN license.
Apply for South Carolina licensure
Submit your license application through the SC Board of Nursing. Processing typically takes 2 to 6 weeks. Many South Carolina employers hire pending license verification.
Top LPN Programs in South Carolina
The following accredited programs are among the most established LPN schools in South Carolina:
| School | City | Duration | Format |
|---|---|---|---|
| Greenville Technical College | Greenville | 12 months | In-person |
| Midlands Technical College | Columbia | 12 months | In-person |
| Trident Technical College | Charleston | 12 months | In-person |
| Florence-Darlington Technical College | Florence | 12 months | In-person |
Program details are subject to change. Verify current offerings directly with each school.
Browse LPN programs in all 50 states
Career Pathways for South Carolina LPNs
Your LPN license in South Carolina opens several advancement routes:
MA to LPN
Already a medical assistant? Bridge programs can fast-track your LPN in 6–12 months.
CNA to LPN
CNAs can earn advanced standing and complete LPN programs faster.
LPN to RN
Advance to Registered Nurse and boost your salary to $86K+ median.
LPN to BSN
Earn your Bachelor of Science in Nursing for the widest career options.
Exploring options in nearby states? Check out LPN programs in North Carolina, Georgia, and Virginia.
Frequently Asked Questions: LPN Programs in South Carolina
How much do LPNs make in South Carolina?
The median LPN salary in South Carolina is $48,470 per year. LPNs in the Charleston metro area earn the most at approximately $50,200, followed by Columbia at $49,100 and Greenville at $48,800. Overtime and shift differentials in hospital and long-term care settings can increase total annual earnings.
How long does it take to become an LPN in South Carolina?
Most South Carolina LPN programs take 12 months to complete as a full-time student. After graduation, you must pass the NCLEX-PN exam and apply for licensure through the SC Board of Nursing, which typically takes an additional 2 to 6 weeks.
What are the best LPN programs in South Carolina?
Greenville Technical College and Midlands Technical College in Columbia are among the top state-approved LPN programs with strong NCLEX-PN pass rates. Trident Technical College in Charleston and Florence-Darlington Technical College also offer well-regarded practical nursing programs throughout the state.
Does South Carolina have online LPN programs?
Some South Carolina LPN programs offer hybrid formats that combine online instruction with required in-person clinical rotations. Fully online LPN programs are not available in South Carolina because clinical hours must be completed at approved healthcare facilities in person.
What does the SC Board of Nursing require for LPN licensure?
The SC Board of Nursing requires completion of an approved practical nursing program, a passing score on the NCLEX-PN exam, a criminal background check, and submission of a license application with fees. South Carolina participates in the Nurse Licensure Compact (NLC), allowing LPNs to practice in other compact states with a single license.
Find LPN Programs in South Carolina
Compare accredited LPN programs near you. Search by location, schedule, and cost to find the right fit.
Last updated: 2026-03-03. Salary data: BLS May 2024 OES, SOC 29-2061.